Lol another alcumus question.
Note that (nk)=(nn−k) or you could just do it the general way. (Same easy)
(223221)=(2232)=223!221!2!=223⋅2222=223⋅111=59393
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Note: I may be tricking you! ;)
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This is to prove if you are just here for the answers or not. All these people put lots of time in this and most people just snatch the answers.